Heart of the Beat (the Flagellar Beat, that Is)
نویسندگان
چکیده
منابع مشابه
Load Response of the Flagellar Beat.
Cilia and flagella exhibit regular bending waves that perform mechanical work on the surrounding fluid, to propel cellular swimmers and pump fluids inside organisms. Here, we quantify a force-velocity relationship of the beating flagellum, by exposing flagellated Chlamydomonas cells to controlled microfluidic flows. A simple theory of flagellar limit-cycle oscillations, calibrated by measuremen...
متن کاملHow molecular motors shape the flagellar beat.
Cilia and eukaryotic flagella are slender cellular appendages whose regular beating propels cells and microorganisms through aqueous media. The beat is an oscillating pattern of propagating bends generated by dynein motor proteins. A key open question is how the activity of the motors is coordinated in space and time. To elucidate the nature of this coordination we inferred the mechanical prope...
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During a normal lifetime, the heart may beat over 2 billion times, but the mechanisms by which the heart beats are initiated remain a subject of intense investigation. Since the discovery of a pacemaker current (I(f)) in 1978, multiple studies have shown that rhythmic changes in membrane voltage (the "membrane voltage clock") underlie the mechanisms of automaticity. The I(f) is a depolarization...
متن کاملBeat Estimation on the Beat
This paper presents a novel method for the estimation of beat interval, and the exact location of the beats from audio files. As a first step, a feature extracted from the waveform is used to identify note onsets. The estimated note onsets are used as input to a beat induction algorithm, where the most probable beat intervals are found. The note onsets corresponding to the beat locations are th...
متن کاملEvidence for axonemal distortion during the flagellar beat of Chlamydomonas.
In order to understand the working mechanism that governs the flagellar beat it is essential to know if the axoneme undergoes distortion during the course of the beat cycle. The rapid fixation method employed by Mitchell was able to preserve the waveform of Chlamydomonas flagella much as it appears during normal flagellar beating [Mitchell, Cell Motil Cytoskeleton 2003;56:120-129]. This conserv...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2009
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2009.09.059